Osteoblastic cell adhesion on Strontium-incorporated porous nanostructured TiO2 coating prepared by micro-arc oxidation

Objective: In the present work, strontium (Sr) was incorporated into TiO2 (Sr-TiO2) coatings on titanium by Micro-arc oxidation (MAO) technique in the Ca, P, Sicontaining electrolyte to obtain the implant with good bioactivity. Methods: The surface topography, phase and element composition were characterized by scanning electron microscopy, X-ray diffraction and energy dispersive spectrometer, respectively. Osteoblast-like Mg63 cells were cultured on the surface of the coatings to evaluate their adhesion behavior. Results: Obtained results showed that compared with the Sr-free TiO2 coating, Sr was successfully incorporated, which did not alter its surface topography and phase composition. Adhesion cells on Sr-incorporated TiO2 coating was significantly enhanced compared with that on the Sr-free TiO2 coating. Conclusion: In conclusion, it is an interesting and promising way to regulate the functions of the coatings by introducing desired elements, such as Sr, by micro-arc oxidation technique.